The use of histone deacetylase inhibitors for the treatment of endometriosis

The use of histone deacetylase inhibitors for the treatment of endometriosis By Murat Osman

Histone deacetylase inhibitors prevent the deacetylation of specific gene sequences thereby allowing the increased transcription of certain genes. Trichostatin A, a histone deacetylase inhibitor, has been seen to induce the expression of a pro-apoptotic gene called nonsteroidal anti-inflammatory drug-activated gene…

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